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Abstract #2429

In-vivo dual-phase cardiac DTI with 3D strain correction

Christian Torben Stoeck 1 , Aleksandra Kalinowska 2 , Constantin von Deuster 1,3 , Jack Harmer 3 , and Sebastian Kozerke 1,3

1 Institute for Biomedical Engineering, University and ETH Zurich, Zurich, Switzerland, 2 Department of Mechanical and Biomedical Engineering, Massachusetts Institute of Technology, Cambridge, MA, United States, 3 Biomedical Engineering and Imaging Sciences, King's College London, London, United Kingdom

Cardiac Diffusion Tensor imaging using the Stimulated Echo Acquisition Mode suffers from inherent myocardial strain effects as diffusion is encoded across 2 R-R intervals. Based on knowledge of the time course of myocardial stretch patterns, diffusion tensor data can be corrected for strain errors. In this work we present a pipeline for deriving stretch tensor fields from three-dimensional myocardial tagging images to correct dual heart phase cardiac DTI data. Upon strain correction, systolic and diastolic fiber architecture acquired in the in-vivo human heart are compared.

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