Abstract #2453

Kelvin Chow ^{ 1 } and Richard B Thompson ^{ 1 }

The MOLLI sequence is commonly used for in-vivo cardiac
T
_{
1
}
mapping
but is known to have systematic errors as a function of
heart rate, flip angle, T
_{
1
}
, and T
_{
2
}
.
We hypothesize that the apparent MOLLI relaxation rate
(R
_{
1
}
^{
*
}
) can be expressed as a time
weighted average (TWA) of the driven relaxation rate
during bSSFP readouts (R
_{
1
}
^{
'
}
) and
the true relaxation rate (R
_{
1
}
) between
readouts. An algebraic expression for R
_{
1
}
^{
*
}
is
presented and validated through Bloch equation
simulations and phantom experiments. The TWA model
analytically describes the effects of many of MOLLIs
sources of error and provides insight into their
interaction.

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