Myocardial T1 mapping at 3T by sampling inversion recovery with real time turboflash
Yanjie Zhu 1 , Yinzhu Gao 1 , Qi Yang 2 , Min Pan 1 , Xin Liu 1 , and Yiu-Cho Chung 1
Paul C. Lauterbur Research Centre for
Biomedical Imaging, Shenzhen Institutes of Advanced
Technology, Chinese Academy of Sciences, Shenzhen,
Xuanwu Hospital Capital Medical University, Beijing,
Myocardial T1 mapping is useful in the diagnosis of
myocardial fibrosis. The MOLLI method is sensitive to
arrhythmia, tissue T2 values etc. and underestimates T1.
We propose an arrhythmia insensitive myocardial T1
mapping technique, IR-rttfl. It performs realtime
turboflash acquisition after an inversion pulse to
sample the recovery of inverted magnetization for about
6 seconds. Diastolic images are selected retrospectively
to estimate T1 map. In phantoms, IR-rttfl was more
accurate than MOLLI. Results from IR-rttfl were
comparable to MOLLI in healthy volunteers and a few
infarct patients. The new technique is useful for robust
myocardial T1 mapping at 3T.
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