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Abstract #2528

Using 3T MRI To Characterize The Early Lesion Of Carotid Vessel Wall In Systemic Lupus Erythematosus Patients With Subclinical Atherosclerosis.

Wei Zhang 1 , Jie Sun 2 , Bin Zhou 1 , Jianrong Xu 1 , Daniel S Hippe 2 , Thomas S Hatsukami 2 , and Chun Yuan 2

1 Department of Radiology, Renji Hospital, Shanghai Jiaotong University School of Medicine, Shanghai, Shanghai, China, 2 Department of Radiology, University of Washington, Seattle, WA, United States

Cardiovascular complications, which result from atherosclerotic lesions, are now the leading cause of mortality in patients with SLE. Subclinical atherosclerosis can be documented in 30% to 40% of patients. An early diagnosis of subclinical AS in young patients with SLE is preferable for a more effective treatment that may reduce the development of major cardiovascular complications. In this study we focus on vessel wall changes on MR imaging to detect early subclinical atherosclerosis lesion in SLE patients and try to find out the risk factors associated with atherosclerosis in these women.

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