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Abstract #2529

Dual Contrast Vessel Wall MRI using Phase Sensitive Polarity Maps

Niranjan Balu 1 , Haining Liu 1 , Shuo Chen 2 , Huijun Chen 2 , Jinnan Wang 3 , Zechen Zhou 1 , and Chun Yuan 1

1 Radiology, University of Washington, Seattle, WA, United States, 2 Biomedical Engineering, School of Medicine,Tsinghua University, Beijing, China, 3 Philips Research North America, Briarcliff Manor, New York, United States

Multicontrast MRI is currently used to identify high-risk atherosclerotic plaque components. We propose a dual contrast vessel wall MRI sequence to identify four major high-risk features: plaque burden, stenosis, intraplaque hemorrhage and juxtaluminal calcification by extending the phase-sensitive reconstruction of a recently proposed vessel wall MRI sequence (SNAP) to include a proton density black-blood weighting. We demonstrate that combined review of bright-blood, gray-blood and black-blood images obtained from a single five minute acquisition can identify high-risk plaque in patients with atherosclerotic carotid plaque.

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