Abstract #2530
Vessel Wall Changes In Patients With Systemic Lupus Erythematosus Compared To Controls: A Preliminary MR Imaging Study In Carotid Artery
Wei Zhang 1 , Jie Sun 2 , Bin Zhou 1 , Jianrong Xu 1 , Daniel S Hippe 2 , Huijun Chen 3 , Thomas S Hatsukami 2 , and Chun Yuan 2
1
Department of Radiology, Renji Hospital,
Shanghai Jiaotong University School of Medicine,
Shanghai, Shanghai, China,
2
Department
of Radiology, University of Washington, Seattle, WA,
United States,
3
Department
of Biomedical Engineering, Tsinghua University, Beijing,
China
Patients with systemic lupus erythematosus (SLE) have
markedly increased risk of carotid atherosclerosis. In
this preliminary study, we tried to use MR imaging and
post-processing software to examine any early
abnormalities in fine structures of carotid vessel wall,
including the wall thickening, different enhancement and
signal intensity changes in patients with SLE by
comparing them to age- and sex-matched controls. MR had
a great success in analysis plaque components, while we
want to show that MR also can be a useful way in
predicting and measuring the early subclinical
atherosclerosis lesion in SLE patients before their
plaque formation.
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