Abstract #2546
Feasibility of volume pulsation measurements of intracranial aneurysms using high-resolution 7T MRI images.
Bram Schermers, BSc 1,2 , Rachel Kleinloog, MD 1 , Bon H Verweij, MD, PhD 1 , Ynte M Ruigrok, MD, PhD 1 , Peter R Luijten, PhD 3 , Fredy Visser 3,4 , Luca Regli, MD, PhD 1,5 , Gabril JE Rinkel, MD 1 , and Jaco J Zwanenburg, PhD 3
1
Brain Center Rudolf Magnus, Department of
Neurology and Neurosurgery, University Medical Center
Utrecht, Utrecht, Utrecht, Netherlands,
2
Faculty
of Science and Technology, Department of Technical
Medicine, University of Twente, Enschede, Twente,
Netherlands,
3
Department
of Radiology, University Medical Center Utrecht,
Utrecht, Netherlands,
4
Philips
Healthcare, Best, Netherlands,
5
Department
of Neurosurgery, University Hospital Zrich, Zrich,
Switzerland
Currently, good predictors for the prediction of
intracranial aneurysm rupture risk are lacking.
Therefore, we assessed the feasibility of measuring
intracranial aneurysm volume pulsation at 7.0 tesla MRI,
and quantified the accuracy of these measurements. Ten
aneurysms were imaged and a phantom-based accuracy study
was performed. We found that noise and intensity
fluctuations due to the inflow of blood have a profound
influence on the accuracy. Though aneurysm pulsation
measurement is feasible in patients, the estimated
inaccuracy is of similar size as the observed volume
pulsations, indicating the need for further improvement
of the image quality protocol and analysis.
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