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Abstract #2553

High-Resolution Diffusion Tensor Imaging (DTI) of the Human Kidneys using a Free-Breathing Multi-Slice Targeted-FOV Approach

Rachel W Chan 1 , Constantin von Deuster 2,3 , Christian T Stoeck 2 , Jack Harmer 3 , Sebastian Kozerke 2,3 , and David Atkinson 1

1 University College London, London, London, United Kingdom, 2 University and ETH Zurich, Zurich, Zurich, Switzerland, 3 King's College London, London, London, United Kingdom

Fractional anisotropy (FA) obtained by diffusion tensor imaging (DTI) can be used to non-invasively assess kidney function. A multi-slice targeted FOV technique that uses a non-coplanar application of excitation and refocusing pulse was extended to free-breathing kidney DTI with a navigator-triggered technique. The purpose of this study was to obtain high-resolution FA and diffusion-tensor maps in healthy subjects who were scanned with two (dual- and single-kidney) targeted FOV scans. The FA maps showed consistency between the two targeted FOVs and across subjects. The medulla and cortical FA values, quantified over multiple contiguous slices, were well-differentiated.

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