Precision and accuracy of intravoxel incoherent motion (IVIM) MRI: applicability in well-perfused tissues

IVIM MRI allows extraction of perfusion and diffusion information from diffusion weighted MR data and is receiving interest for use in well-perfused organs. Monte Carlo simulations were used to investigate the precision and accuracy of IVIM parameter estimation. To achieve acceptable precisions, unrealistically high SNRs are required for perfusion fractions typical of brain. At perfusion fractions typical of well-perfused organs, acceptable precisions and accuracies can be achieved with realistic SNRs. However, at high perfusion fractions systematic errors may become more prominent.

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