Precision and accuracy of intravoxel incoherent motion (IVIM) MRI: applicability in well-perfused tissues
Mie Kee Lam 1 , Clemens Bos 1 , Chrit T W Moonen 1 , Max A Viergever 1 , and Lambertus W Bartels 1
Image Sciences Institute, UMC Utrecht,
Utrecht, Utrecht, Netherlands
IVIM MRI allows extraction of perfusion and diffusion
information from diffusion weighted MR data and is
receiving interest for use in well-perfused organs.
Monte Carlo simulations were used to investigate the
precision and accuracy of IVIM parameter estimation. To
achieve acceptable precisions, unrealistically high SNRs
are required for perfusion fractions typical of brain.
At perfusion fractions typical of well-perfused organs,
acceptable precisions and accuracies can be achieved
with realistic SNRs. However, at high perfusion
fractions systematic errors may become more prominent.
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