Abstract #2577

Investigation of artificial increase of fractional anisotropy (FA) due to truncation artifact in DTI data and compensation using total variation constrained data extrapolation

Daniel Gllmar ¹ , Ferdinand Schweser ¹ , and Jrgen R Reichenbach ¹

¹ Medical Physics Group, Institute of Diagnostic and Interventional Radiology I, Jena University Hospital - Friedrich Schiller University Jena, Jena, Germany

Artificial increase in fractional anisotropy occurs due to truncation artifacts in b0 (unweighted) images in DTI data. This artifact can be reduced using total variation constrained data extrapolation. Uncorrected and corrected data were used to obtain FA maps and the differences were investigated in a detailed ROI based analysis. This analysis showed a clear dependence of the artifact with respect to pial surface distance as expected from the theory.

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