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Abstract #2596

The Performance of NODDI Estimation Using a Common 2-Shell Protocol

Zhen Wang 1 , Yuan Wang 1 , Jianye Zhang 1 , Xu Yan 2 , Hui Liu 2 , and Zeping Xiao 1

1 Shanghai Mental Health Center, Shanghai, China, 2 MR Collaboration NE Asia, Siemens Healthcare, Shanghai, China

The study tested the estimation accuracy of Neurite orientation dispersion and density imaging (NODDI) using a common 2-shell protocol with the same gradient direction at each shell. The experiment used visual and quantitative comparisons to demonstrate that the common 2-shell protocol had very similar performance as the optimized NODDI protocol, but is easy to configure in a commercial scanner, thus can be widely adopted in clinical study.

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