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Abstract #2614

Experimental considerations for OGSE of anisotropic tissue

Henrik Lundell 1 , Casper Kaae Snderby 1 , and Tim B Dyrby 1

1 Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark

Oscillating gradient spin echo (OGSE) experiments offers new insight in tissue microstructure by probing diffusion processes on ultra-short time scales. In this study we examine different possibilities for sampling OGSE on anisotropic tissue. We find that the best results for very limited gradient strength is achieved with square/trapezoidal gradients in 6 gradients, whereas a circularly polarized OGSE (CP-OGSE) perform better at higher gradient strengths. Our results emphasize that the optimal solution is highly dependent on the given limitations and the parameters of interest.

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