Abstract #2645
Regional change in DTI parameters due to scanner upgrade: effects on TBSS and ROI analysis
Petra Pouwels 1 , Frederik Barkhof 2 , Rudolf Verdaasdonk 1 , and Joost Kuijer 1
1
Physics & Medical Technology, VU University
Medical Center, Amsterdam, Netherlands,
2
Radiology
and Nuclear Medicine, VU University Medical Center,
Amsterdam, Netherlands
Regional changes in DTI parameters were observed in
healthy volunteers at 3T after a hardware upgrade.
Pairwise comparison (mimicking longitudinal studies)
showed significant FA differences in 26.7% of the WM
skeleton, and in all diffusivities, especially in the
body of the corpus callosum. Unpaired comparison
(mimicking cross-sectional studies) still showed FA
differences in 5.5% of the skeleton. A change in
gradient system and related eddy-current behaviour might
be the cause of the observations. No pairwise
differences were observed in repeated measurements on
the same scanner. These results emphasize the need to
take scanner upgrade into account in the study design.
How to access this content:
For one year after publication, abstracts and videos are only open to registrants of this annual meeting. Registrants should use their existing login information. Non-registrant access can be purchased via the ISMRM E-Library.
After one year, current ISMRM & ISMRT members get free access to both the abstracts and videos. Non-members and non-registrants must purchase access via the ISMRM E-Library.
After two years, the meeting proceedings (abstracts) are opened to the public and require no login information. Videos remain behind password for access by members, registrants and E-Library customers.
Click here for more information on becoming a member.
