Abstract #2648
Quantitative evaluation of biophysical models of the diffusion with in vivo data by assessment of the generalization error
Benoit Scherrer 1 , Maxime Taquet 1 , Mustafa Sahin 2 , Sanjay P Prabhu 1 , and Simon K. Warfield 1
1
Radiology, Harvard Medical School, Boston
Children's Hospital, Boston, MA, United States,
2
Neurology,
Harvard Medical School, Boston Children's Hospital,
Boston, MA, United States
We propose a novel framework to achieve quantitative
evaluation of biophysical models of the diffusion with
in-vivo data. It enables identification of the model
that best predicts the diffusion signal, and therefore
identification of the model that best captures the
underlying biophysical mechanisms. We investigate the
performance of DTI, NODDI and DIAMOND.
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