Abstract #2649
Do DTI reproducibility studies agree? A meta-analysis.
Pim Pullens 1 , Wim van Hecke 2 , and Paul M Parizel 1
1
Radiology, Antwerp University Hospital,
Edegem, Antwerp, Belgium,
2
Icometrix,
Leuven, Belgium
There is more and more interest in testing
reproducibility of DTI measures, which could lead to use
of DTI measures as clinical biomarkers. Coefficient of
variation (std/mean) is often used to assess
reproducibility. However, it is not trivial to compare
CVs from different studies, each with a different number
of subjects. In this meta-analysis across DTI
reproducibility studies, we test if CVs are equal among
published FA reproducibility studies with an appropriate
statistical test. Results show that although confidence
intervals of FA show deviations because of analysis or
scanner type, CVs are comparable.
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