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Abstract #2659

Progression of Whole Mouse Brain Formaldehyde Fixation by T2 and ADC Maps

Tiziana M Florio 1 , Giuseppina Confalone 1 , Loredana Cristiano 1 , Alessia Fidoamore 1 , Angelo Galante 1,2 , Laura Brandolini 3 , Marcello Allegretti 3 , Annamaria Cimini 1 , and Marcello Alecci 1,2

1 Dipartimento Medicina Clinica, Sanita Pubblica, Scienze della Vita e dell'Ambiente, University of L'Aquila, L'Aquila, Italy, 2 Istituto Nazionale di Fisica Nucleare, Laboratori Nazionali del Gran Sasso, Italy, 3 Research Centre, Domp pha.r.ma s.p.a., L'Aquila, Italy

We have investigated the time course from sacrifice of ADC and T2 maps of whole mouse brain during fixation with formaldehyde, comparing the immersion and perfusion methods. A non-fixed whole brain was studied for comparison.

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