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Abstract #2658

Diffusion gradient calibration in DSI using a cyclooctane phantom

Irvin Teh 1 , Maelene Lohezic 1 , Dunja Aksentijevic 1,2 , and Jurgen E Schneider 1

1 Division of Cardiovascular Medicine, Radcliffe Department of Medicine, University of Oxford, Oxford, United Kingdom, 2 Cardiovascular Division, The Rayne Institute, King's College London, London, United Kingdom

Gradient calibration is critical to accurate sampling of q-space in diffusion MRI, particularly for applications such as diffusion spectrum imaging (DSI) that rely on a precise relationship of q-space sampling. Cyclooctane possesses a number of properties that make it suitable for gradient calibration at high b-values, including isotropic diffusion, relatively low diffusivity and high viscosity, and a single proton resonance. We present the novel use of a phantom intended for gradient calibration in DSI and other high b-value q-space imaging applications.

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