Abstract #2657
Quality Assurance for Multi-Center DTI Trial at 3T
Xiaopeng Zhou 1 , Ken Sakaie 1 , Erik Beall 1 , Mark Lowe 1 , and Robert Fox 2
1
Imaging Institute, Cleveland Clinic,
Cleveland, OH, United States,
2
Neurological
Institute, Cleveland Clinic, Cleveland, OH, United
States
We describe the development of a practical quality
assurance (QA) protocol for a multi-center diffusion
tensor imaging trial. fBIRN phantom was scanned on two
3T scanners to evaluate temporal stability of SNR and
DTI parameters. Robustness of QA metrics against
positioning provides confidence that the protocol will
be effective across sites. Although variation of tensor
parameters is small, it does correlate with SNR,
suggesting that QA measurements may serve as a valuable
covariate for statistical analysis. Tensor parameters
appear consistent across platforms. This DTI QA
procedure is effective to track scanner performance and
can provide reference for multi-center trial.
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