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Abstract #2657

Quality Assurance for Multi-Center DTI Trial at 3T

Xiaopeng Zhou 1 , Ken Sakaie 1 , Erik Beall 1 , Mark Lowe 1 , and Robert Fox 2

1 Imaging Institute, Cleveland Clinic, Cleveland, OH, United States, 2 Neurological Institute, Cleveland Clinic, Cleveland, OH, United States

We describe the development of a practical quality assurance (QA) protocol for a multi-center diffusion tensor imaging trial. fBIRN phantom was scanned on two 3T scanners to evaluate temporal stability of SNR and DTI parameters. Robustness of QA metrics against positioning provides confidence that the protocol will be effective across sites. Although variation of tensor parameters is small, it does correlate with SNR, suggesting that QA measurements may serve as a valuable covariate for statistical analysis. Tensor parameters appear consistent across platforms. This DTI QA procedure is effective to track scanner performance and can provide reference for multi-center trial.

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