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Abstract #2662

The reproducibility of diffusion tensor imaging on brain connectivity measures between cortical regions using probabilistic tractography

Chun-Hao Huang 1 , Woan-Chyi Wang 2 , Yi-Ru Lin 1 , and Shang-Yueh Tsai 2

1 Electronic and Computer Engineering, National Taiwan University of Science and Technology, Taipei, Taiwan, 2 Graduate Institute of Applied Physics, National Chengchi University, Taipei, Taiwan

In this study we investigate the reproducibility of DTI and probabilistic tractography on the brain connectivity measures among 78 grey matter parcellations. Regular DTI protocols (30 directions, b=1000) were performed twice on each 14 healthy subject (7 male and 7 female in 20 to 25 years old). Results show that probabilistic tractography can be successfully applied to calculate the connectivity between GM regions. The inter-scan reproducibility is at level of 10% for GM regions with connectivity strength over 0.2. Therefore, structural connectivity assessed by diffusion tensor tractogrphy can be used to study the brain network.

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