Abstract #2666
Phantomas: a flexible software library to simulate diffusion MR phantoms
Emmanuel Caruyer 1 , Alessandro Daducci 2 , Maxime Descoteaux 3 , Jean-Christophe Houde 3 , Jean-Philippe Thiran 2 , and Ragini Verma 1
1
Section of Biomedical Image Analysis,
Department of Radiology, University of Pennsylvania,
Philadelphia, PA, United States,
2
Signal
Processing Laboratory 5, cole Polytechnique Fdrale de
Lausanne, Lausanne, Vaud, Switzerland,
3
Sherbrooke
Connectivity Imaging Lab, Universit de Sherbrooke,
Sherbrooke, Qubec, Canada
We introduce Phantomas, an open-source software library
to create realistic phantoms in structural and diffusion
MRI. The software allows evaluation of each step of a
tractography processing pipeline: acquisition design,
preprocessing, local reconstruction and tractography
algorithm. By starting from a ground truth configuration
of fiber bundle geometries, Phantomas provides a basis
to quantitatively evaluate connectivity analyses, using
metrics based on successful reconstruction of the true
connectivity profile. Complementarily, local metrics can
be computed to measure the accuracy of local
reconstruction methods. We demonstrate that user can
easily create crossing, kissing and bending fiber
configurations, leading to complex intravoxel diffusion
profiles.
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