Abstract #2667
Lateralization of Temporal Lobe Epilepsy using Intrinsic Property of Water Diffusion in Fornix Crus
Mohammad-Reza Nazem-Zadeh 1 , Jason Schwalb 2 , Hassan Bagher-Ebadian 3 , Fariborz Mahmoudi 1 , Mohammad-Parsa Hosseini 4 , Hajar Hamidian 1 , Abdelrahman Hassane 1 , Oltion Meci 1 , Harrini Vijay 1 , Mohammad Emari 1 , and Hamid Soltanian-Zadeh 1
1
Radiology and Research Administration
Departments, Henry Ford Hospital, Detroit, MI, United
States,
2
Neurosurgery
Department, Henry Ford Hospital, Detroit, MI, United
States,
3
Neurology
Department, Henry Ford Hospital, Detroit, MI, United
States,
4
Radiology
and Research Administration Departments, Henry Ford
Hospital, MI, United States
We hypothesizes that the hemispheric asymmetry of FA
within the crura of fornix could be used to confirm the
laterality of mesial temporal epileptogenicity. The TLE
was associated with a reduced FA value in the fornix
crus ipsilateral to the seizure onset. Outperforming
anatomy-based lateralization methods, the proposed
diffusion based method hold promise for improving
decision-making for surgical resection and may reduce
the need for implantation of intracranial monitoring
electrodes.
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