Meeting Banner
Abstract #2683

Leukoencephalopathy in acute CO intoxication: Diffusion kurtosis versus diffusivity

Ping-Huei Tsai 1,2 , Ming-Chung Chou 3 , Cheng-Yu Chen 1,2 , Shih-Wei Chiang 4,5 , Chao-Ying Wang 5 , Hsiao-Wen Chung 4 , Hung-Wen Kao 5 , and Yi-Hsiu Hsiao 1

1 Imaging Research Center, Taipei Medical University, Taipei, Taiwan, 2 Department of Medical Imaging, Taipei Medical University Hospital, Taipei Medical University, Taipei, Taiwan, 3 Department of Medical Imaging and Radiological Sciences, Kaohsiung Medical University, Kaohsiung, Taiwan, 4 Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan, 5 Department of Radiology, Tri-Service General Hospital, National Defense Medical Center, Taipei, Taiwan

Acute CO intoxication is one of the most common lethal poisons worldwide, and could lead to brain injury resulting from leukoencephalopathy. Although diffusion tenor (DT) related parametric maps could help assess the brain structural changes resulting from demyelination, it may not be highly sensitive to observe the subtle alternations in patients with acute CO intoxication. The purpose of this study is to validate evaluate the ability of diffusion kurtosis imaging (DKI) for early detection of the brain WM microstructural changes. The present finding indicated that the use of DKI method may provide some valuable information in prediction of leukoencephalopathy in these patients.

This abstract and the presentation materials are available to members only; a login is required.

Join Here