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Abstract #2694

31P DWS of different muscles in the lower leg

Melissa Hooijmans 1 , Ece Ercan 1 , Robert Brandt 1 , Andrew Webb 1 , Hermien Kan 1 , and Itamar Ronen 1

1 Radiology, Leiden University Medical Center, Leiden, Zuid-holland, Netherlands

Conventional diffusion weighted imaging is limited by the lack of compartment specificity of water. In this work, we show the application of 31P diffusion weighted spectroscopy of individual muscles in the lower leg at 7T. SNR was sufficient to determine apparent diffusion coefficients of phosphocreatine (PCr) in two different muscles of the leg. In conclusion we are able to assess the diffusion of PCr in the individual lower leg muscles and these values seem to be affected more by cell size than fiber type distribution.

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