Single-Artery Pseudo-Continuous Arterial Spin Labeling with Off-Resonance Correction

The single-artery, or vessel-selective, pCASL sequence has demonstrated to provide regional perfusion maps non-invasively. However, similar to the original pCASL labeling, vessel-selective pCASL is also sensitive to off-resonance effects, which introduce phase errors in the labeling RF train and thus compromise in tagging efficiency. In this work, we propose to restore the signal loss due to off-resonance effects by applying a modified multiple phase correction method in the vessel-selective labeling sequence.

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