Abstract #2701
Improving perfusion quantification in Arterial Spin Labeling for delayed arrival times by using optimized acquisition schemes
Johanna Kramme 1 , Johannes Gregori 2 , Volker Diehl 1,3 , Vince Istvan Madai 4,5 , Federico C von Samson-Himmelstjerna 1,4 , Markus Lentschig 3 , Jan Sobesky 4,5 , and Matthias Gnther 1,6
1
Fraunhofer MEVIS, Bremen, Bremen, Germany,
2
Mediri
GmbH, Heidelberg, Germany,
3
ZEMODI,
Bremen, Germany,
4
Center
for Stroke Research Berlin, Charit Universittsmedizin,
Berlin, Germany,
5
Department
of Neurology, Charit Universittsmedizin, Berlin,
Germany,
6
University
of Bremen, Bremen, Germany
SNR loss due to T1 decay at long TIs can be partly
compensated by redistributing the acquisition schemes,
resulting in improved perfusion quantification
especially for patients with prolonged BATs. Varies
redistribution schemes are presented where the number of
averages is reduced at short TIs and increased at long
once. The impact of the redistribution on perfusion
estimation in cases of long BAT is studied and compared
to the standard acquisition method. Such a correction is
of high clinical relevance in cerebrovascular diseases
or elderly patients showing prolonged BAT, as
demonstrated in patients and in comparison to
volunteers.
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