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Abstract #2776

Cerebral Angiography in Rats: Comparison of 1 H TOF-MRA, SPIO Enhancement and Hyperpolarized 13 C bSSFP

Kasper Wigh Lips 1,2 , Peter Magnusson 1 , Lise Vejby Sgaard 1 , and Jan Henrik Ardenkjr-Larsen 2,3

1 Danish Research Centre for Magnetic Resonance, Copenhagen University Hospital Hvidovre, Hvidovre, Denmark, 2 Department of Electrical Engineering, Technical University of Denmark, Kgs. Lyngby, Denmark, 3 GE Healthcare, Brndby, Denmark

We compare non-contrast enhanced MRA, SPIO enhanced MRA and hyperpolarized 13 C MRA in rat cerebral regions, and demonstrate how venous structures can be imaged with acquisition times less than a second. We describe optimized sequence designs for each of the techniques. The hyperpolarized 13 C shows promising results for angiographic imaging where short acquisition time is essential, such as imaging within a single heartbeat or breath hold.

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