Ferumoxytol labeling of human neural progenitor cells for tracking with MRI in the porcine spinal cord
Jason Lamanna 1,2 , Juanmarco Gutierrez 2 , Lindsey Urquia 2 , Natalia Grin 2 , Jonathan Riley 2 , Jaclyn Espinosa 3 , Thais Buchman 2 , John Oshinski 4 , and Nicholas Boulis 2
Biomedical Engineering, Emory University and
Georgia Institute of Technology, Atlanta, GA, United
Emory University, Atlanta, GA, United States,
Emory University, GA, United States,
Emory University, GA, United States
Clinical investigations of cell-based therapies
transplanted in to the spinal cord do not have a
reliable method of confirming graft delivery or
survival. We demonstrate a straightforward approach to
label human neural progenitor cells with ferumoxytol and
track them in the spinal cord of a large animal.
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