Assessment of bone marrow adipose tissue and glucose metabolism in a whole body MR/PET system: distribution patterns and correlation with anthropometric data
Nina F Schwenzer 1 , Marinus Schmid 1 , Sergios Gatidis 1 , Holger Schmidt 1,2 , Cornelia Brendle 1 , Christian la Fougre 3 , Claus D Claussen 1 , Christina Pfannenberg 1 , and Christina Schraml 1
Diagnostic and Interventional Radiology,
Dept. of Radiology, University Hospital Tbingen,
Tbingen, BW, Germany,
Imaging and Radiophramacy, Dept. of Radiology,
University Hospital Tbingen, BW, Germany,
Medicine, Dept. of Radiology, University Hospital
Tbingen, Tbingen, BW, Germany
Recently introduced whole body MR/PET systems allow for
assessment of MR- and PET-information within one
examination. Furthermore, characterization of tissue
properties is possible with high alignment quality of
PET and MRI. In the present study, the composition and
glucose utilization of bone marrow throughout the human
skeleton in vivo was assessed with respect to the fat
content using a simultaneous MR/PET scanner.
Additionally, the correlation with anthropometric and
endocrinological factors on bone marrow composition and
metabolic activity such as age, body mass index and
blood glucose level were analyzed.
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