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Abstract #2826

Artifacts in the segmentation-based attenuation correction of MR/PET and their impact on PET quantification

Cornelia Brendle 1 , Holger Schmidt 2 , Anja Oergel 1 , Ilja Bezrukov 2 , Mark Mueller 3 , Christina Pfannenberg 1 , and Nina Schwenzer 1

1 Radiology, Tuebingen, Baden-Wuerttemberg, Germany, 2 Preclinical Imaging, Tuebingen, Baden-Wuerttemberg, Germany, 3 Nuclear Medicine, Tuebingen, Baden-Wuerttemberg, Germany

In this study the routinely used segmentation-based PET attenuation correction map in hybrid MR/PET was analyzed concerning artifacts in general and in suspicious PET positive lesions as well as their impact on PET quantification. Nearly 3 artifacts were found per patient dataset with significant changes of PET quantification in the lungs, at the body contours, around metal implants and in the brain. PET positive lesions especially around metal implants resulted in significant changes of PET quantification. We recommend checking attenuation correction maps for artifacts in routine MR/PET examinations in order to avoid impairment of lesion characterization and differentiation.

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