Abstract #2877
Partial volume correction of 1 H brain CSI by grid shifting (PANGS)
Yi Zhang 1,2 , Jinyuan Zhou 1,3 , and Paul Bottomley 1,2
1
Department of Radiology, Johns Hopkins
University, Baltimore, MD, United States,
2
Department
of ECE, Johns Hopkins University, Baltimore, MD, United
States,
3
F.M.
Kirby Research Center for Functional Brain Imaging,
Kennedy Krieger Institute, Baltimore, MD, United States
The low spatial resolution typical of chemical shifting
imaging (CSI) studies causes partial volume errors and
signal bleed, especially in voxels near the scalp. The
standard solution is to apply spatial apodization
filters, which adversely affect spatial resolution.
Here, a novel automated strategy for partial volume
correction employing grid shifting (PANGS), is presented
that minimizes partial volume bleed without compromising
spatial resolution. PANGS is applied to significantly
reduce lipid artifacts in 1H brain CSI and metabolite
maps, and to improve metabolite detection in cortical
regions.
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