Abstract #2882
A Fully Automated and Robust Method of Extracting CSI voxels from Precise Anatomical Locations: An Application to a Longitudinal P MRS Study
Helen Wu 1 , Dhruman Goradia 2 , and Jeffrey Stanley 2
1
Psychiatry and Behavioral Neurosciences,
Wayne State University School of Medicine, Detroit, MI,
United States,
2
Psychiatry
and Behavioral Neurosciences, Wayne State University
School of Mediciney, Detroit, MI, United States
When using a 1H or 31P multi-voxel technique for
detecting biochemical changes in longitudinal studies,
the precise and consistent voxel placement at desired
anatomical regions of interest is frequently a great
challenge. Here we propose a novel method which takes
advantage of the ability to re-shift the CSI voxel grid
after data has been collected as well as orientation
information provided by same-session volumetric T1 image
sets. This fully automated method is able to
systematically place voxels in pre-defined anatomical
locations, after which MRS signals are extracted from
those voxels for quantification.
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