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Abstract #2888

Analysis of proton MRSI metabolites with improved tissue segmentation at 7T

Yoojin Lee 1 , Tae Kim 1 , Tiejun Zhao 2 , Jullie W. Pan 1 , and Hoby P. Hetherington 1

1 Department of Radiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States, 2 Siemens Medical Solution USA, INC., Siemens MediCare USA, Pittsburgh, Pennsylvania, United States

In this study, we use B1 inhomogeneity correction method in MPRAGE image to improve tissue segmentation at 7T and apply this accurate segmentation result for more precise metabolic analysis for MRSI. The data set of percent GM from segmentation results and Cr/NAA from MRSI data was used for linear regression analysis. The patient data was also acquired and compared with the linear regression result of normal subject data.

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