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Abstract #2903

DRESS-localized dynamic 31 P-MRS of the exercising human gastrocnemius muscle at 7T

Ladislav Valkovic 1,2 , Barbara Ukropcov 3,4 , Marek Chmelk 1 , Ivica Just Kukurov 1 , Timea Kurdiov 3 , Monika Christina Kipfelsberger 1 , Patrik Krumpolec 3 , Wolfgang Bogner 1 , Martin Meyerspeer 5 , Ivan Frollo 2 , Iwar Klimes 3 , Jozef Ukropec 3 , Siegfried Trattnig 1 , and Martin Krssk 1,6

1 High Field MR Centre, Department of Biomedical Imaging and Image-guided Therapy, Medical University of Vienna, Vienna, Austria, 2 Department of Imaging Methods, Institute of Measurement Science, Slovak Academy of Sciences, Bratislava, Slovakia, 3 Obesity Section, Diabetes and Metabolic Disease Laboratory, Institute of Experimental Endocrinology, Slovak Academy of Sciences, Bratislava, Slovakia, 4 Institute of Pathophysiology, Faculty of Medicine, Commenius University, Bratislava, Slovakia, 5 Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria, 6 Division of Endocrinology and Metabolism, Department of Internal Medicine III, Medical University of Vienna, Vienna, Austria

In this study, a performance of the depth resolved surface coil MRS (DRESS) sequence was assessed in exercising gastrocnemius muscle at 7T. Two dynamic examinations (one non-localized and one DRESS-localized) were performed and the measured metabolic parameters were compared. Significantly higher PCr drop and no Pi split in the DRESS localized spectra point towards good 31 P signal localization from the gastrocnemius muscle.

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