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Abstract #2904

High-resolution free induction decay proton MRSI in the human brain at 9.4 T

Grzegorz L. Chadzynski 1,2 , Anke Henning 2,3 , Philipp Ehses 1,2 , Jens Hoffmann 2 , G. Shajan 2 , and Klaus Scheffler 1,2

1 Biomedical Magnetic Resonance, University Hospital Tuebingen, Tuebingen, Germany, 2 High-Field Magnetic Resonance Center, Max Planck Institute for Biological Cybernetics, Tuebingen, Germany, 3 Institute for Biomedical Engineering, University and ETH Zuerich, Zuerich, Switzerland

The FID-MRSI technique is a promising tool to be used for spectroscopic imaging at ultra-high magnetic field as it enables short TE and avoids in-plane chemical shift displacement. However, due to the acquisition delay, the first points of the acquired FID signals are missing, giving rise to phase problems which may hamper quantitative analysis. Our aim was to examine the feasibility of high-resolution FID-MRSI of the healthy human brain at the field strength of 9.4 T. The missing FID points were reconstructed with an autoregressive model so that the phase problems present in the acquired spectra could be minimized.

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