Proton relaxation times of human prostate metabolites at 3 T

Proton single-voxel PRESS magnetic resonance spectroscopy of the human prostate at 3 T was performed using a surface coil. The aim of the study was estimation prostate water, choline, creatine, and citrate relaxation times T1, T2. Spectra were processed by LCModel and AMARES algorithms. T1 and T2 values were obtained by mono-exponential fitting of the spectral intensities versus repetition or echo times. Knowledge of the relaxation times enables quantification of prostate metabolite concentrations using water as the internal concentration reference.

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