Meeting Banner
Abstract #2927

Simultaneous 19 F MR imaging at different resonance frequencies using multi chemical shift selective RARE

Christoph Jacoby 1 , Thomas Oerther 2 , Sebastian Temme 1 , Jrgen Schrader 1 , and Ulrich Flgel 1

1 Molecular Cardiology, Heinrich Heine University, Dsseldorf, NRW, Germany, 2 Bruker BioSpin GmbH, Rheinstetten, Baden-Wrttemberg, Germany

In the present study a multi chemical shift selective (MCSS) RARE sequence was used for artifact-free 19 F MR imaging of perfluorocarbons (PFC) with complex spectra and compared to conventional methods in terms of sensitivity and quantifiability. Reliable quantification was demonstrated by simultaneous imaging of various mixtures of different PFC emulsions ex vivo and in vivo . The average enhancement factor was determined to be more than two-fold as compared to single excitation RARE without any loss of information due to intrinsic spatial averaging mechanisms. MCSS-RARE may also be useful for other nuclei, e.g. simultaneous imaging of all phosphorus of ATP.

This abstract and the presentation materials are available to members only; a login is required.

Join Here