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Abstract #2951

In vivo spectroscopic imaging of N-acetyl-aspartyl-glutamate (NAAG) in human brain at 3.0 T: Reproducibility and regional variation study

Sandeep K Ganji 1,2 , Akshay Madan 1 , Zhongxu An 1 , and Changho Choi 1,2

1 Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States, 2 Radiology, UT Southwestern Medical Center, Dallas, TX, United States

We report in vivo spectroscopic imaging of N-acetyl aspartyl glutamate (NAAG) at 3T using PRESS-based localization method. We present in vivo data from five healthy volunteers. Repeatability, reproducibility results and linear regression with white matter fraction are also reported. Metabolites concentration maps are presented to visualize the regional distribution.

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