Abstract #3009
The Duration and Extent of effects of Neuronavigated Low-Frequency rTMS to Primary Motor Cortex using fMRI in Healthy Subjects
Seong-Uk Jin 1 , Jang Woo Park 1 , Jeehye Seo 1 , Jong Su Baeck 1 , Mun Han 1 , Kyung Eun Jang 1 , and Yongmin Chang* 1,2
1
Department of Medical & Biological
Engineering, Kyungpook National University, Daegu,
Korea,
2
Department
of Molecular Medicine & Diagnostic Radiology, Kyungpook
National University, Daegu, Korea
Neuronavigated low-frequency repetitive transcranial
magnetic stimulation is known to produce local and
interhemisperic neuromodulatory effects on cortical
excitability with accuracy in targeting of a given
cortical region. However there have been few studies
about the duration and extent of neuromodulatory effect
in neuronavigated rTMS using functional magnetic
resonance image (fMRI). Navigated rTMS on primary motor
cortex lead to robust modulation not only at the
ipsilateral motor network, but also at the contralateral
(unstimulated) hemisphere for more than 20 minutes. Our
findings highlight the duration and extent of
interhemispheric neuromodulation effects of rTMS with
serial consecutive fMRI for the first time.
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