Abstract #3026
Auditory Midbrain Encoding of Ultrahigh Frequency Sound
Patrick P. Gao 1,2 , Jevin W. Zhang 1,2 , Iris Y. Zhou 1,2 , Joe S. Cheng 1,2 , Dan H. Sanes 3 , and Ed X. Wu 1,2
1
Laboratory of Biomedical Imaging and Signal
Processing, The University of Hong Kong, Hong Kong,
HKSAR, China,
2
Department
of Electrical and Electronic Engineering, The University
of Hong Kong, Hong Kong, HKSAR, China,
3
Department
of Biology, New York University, New York, NY, United
States
Ultrahigh frequencies (UHFs) are important for social
communication of many species (e.g. higher than 40/60
kHz for rats/mice, respectively). While lower
frequencies are known to be represented as tonotopy in
the auditory system, it remains largely unclear how the
UHFs are encoded and processed. In the auditory pathway,
the inferior colliculus (IC) is a midbrain nucleus
targeted by both ascending and descending auditory
projections, thus a key station for auditory information
processing. In this study, non-invasive BOLD fMRI was
applied to investigate the underlying mechanisms of UHF
encoding in the IC.
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