Meeting Banner
Abstract #3032

Study of the linearity in BOLD response in spinal fMRI

Michela Fratini 1 , Marta Moraschi 1,2 , Bruno Maraviglia 1 , Federico Giove 1,3 , Paul Summers 4 , Stefania Favilla 4 , and Carlo Adolfo Porro 4

1 Fermi Center, Rome, Rome, Italy, 2 Fondazione Santa Lucia, Rome, Italy, 3 Dipartimento di Fisica, Sapienza Universita` di Roma, Rome, Italy, 4 Dipartimento di Scienze Biomediche, Univ. Modena e Reggio Emilia, Modena, Italy

Spinal cord fMRI may be of immediate application in neuroradiology, and in particular for the assessment and follow-up of spinal injuries, pain, and neurodegenerative diseases. However, the exact features of functional response, and the biophysical origin of the signal, are still unclear. In this framework, we parametrically studied the connection between stimulation strength and functional response using controlled motor task (isometric task). We observe a strong parametric dependence of functional response in the spinal cord on the stimulation strength. Such a dependence confirms the physiological origin of the response, and is of great help in model-based fMRI inference.

This abstract and the presentation materials are available to members only; a login is required.

Join Here