Perfusion changes associated with real-time fMRI neurofeedback training targeting motor cortex

This preliminary study investigated perfusion changes associated with real-time fMRI neurofeedback training targeting motor cortex. Six right-handed healthy volunteers underwent five days neurofeedback training to self-regulate the brain activity within the left motor cortex using the finger tapping imagery task for the dominant right hand. Pre- to post-training comparison revealed increased CBF in the left motor and somatosensory cortex as well as the visual cortex but decreased CBF in the right anterior dorsolateral prefrontal cortex (DLPFC), which might provide interesting insight into the mechanism of neurofeedback training.

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