Abstract #3044
Auditory fMRI study of frequency-modulation direction selectivity in the rat subcortex
Joe S. Cheng 1,2 , Jevin W. Zhang 1,2 , Patrick P. Gao 1,2 , Adrian Tsang 1,2 , Iris Y. Zhou 1,2 , and Ed X. Wu 1,3
1
Department of Electrical and Electronic
Engineering, the University of Hong Kong, Hong Kong,
Hong Kong,
2
Laboratory
of Biomedical Imaging and Signal Processing, the
University of Hong Kong, Hong Kong, Hong Kong, Hong
Kong,
3
Laboratory
of Biomedical Imaging and Signal Processing, the
University of Hong Kong, hong kong, Hong Kong, Hong Kong
The direction of frequency-modulation (FM) sweep is an
important acoustic cue for human language and animal
vocal communications. To investigate FM direction
processing in development and disease models, an in vivo
and non-invasive technique with high spatial resolution
is desired. Therefore, we investigated the FM direction
selectivity in the rat subcortex using. The BOLD signal
changes during upward sweeps were significantly higher
than those during downward sweeps in the dorsal CIC,
while dorsal nuclei of later lemniscus didnt show any
directional selectivity. Therefore, fMRI proves a
feasible tool to probe the FM sweep direction
selectivity in the subcortical structures.
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