Abstract #3074
Altered resting-state functional connectivity of cerebellum in Parkinson's disease
Hu Liu 1 , Guoguang Fan 1 , and Ke Xu 1
1
Department of Radiology, The First
Affiliated Hospital of China Medical University,
Shenyang, Liaoning, China
An improved understanding of the cerebellum, especially
the cerebello-thalamo-cortical (CTC) circuit in
Parkinsons disease (PD)-related changes, is essential
for a better understanding of the pathophysiology of the
disorder. Previous study describes a relationship
between the anterior lobe of the cerebellum and motor
function, and between the posterior lobe and executive
function. Using functional connectivity method we found
increased functional connectivity of the cerebellar
posterior lobe in the resting state. This alteration may
play a compensatory role in cognitive or executive
functions of PD patients.
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