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Abstract #3108

Magnetohydrodynamic effects in MRI studies of ionic-current phantoms: dependence on field strength and conductivity

Mukund Balasubramanian 1 , Robert V. Mulkern 1 , William M. Wells 2 , Padmavathi Sundaram 1 , and Darren B. Orbach 1

1 Department of Radiology, Boston Children's Hospital, Boston, Massachusetts, United States, 2 Department of Radiology, Brigham and Women's Hospital, Boston, Massachusetts, United States

Understanding the behavior of ionic volume currents in strong magnetic fields could facilitate efforts to use MRI to detect signals more tightly coupled to neuronal activity. However, studies on this topic are controversial: two competing mechanisms have been proposed to account for the behavior of these currents. One of these mechanisms, magnetohydrodynamic flow, predicts a slow evolution of phase signals (on the order of one minute for 0.9% saline at 3T) that is dependent on both field strength and conductivity. Here, we test and confirm these predictions using 0.9% and 3.6% saline current phantoms scanned at 1.5T and 3T.

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