Magnetohydrodynamic effects in MRI studies of ionic-current phantoms: dependence on field strength and conductivity
Mukund Balasubramanian 1 , Robert V. Mulkern 1 , William M. Wells 2 , Padmavathi Sundaram 1 , and Darren B. Orbach 1
Department of Radiology, Boston Children's
Hospital, Boston, Massachusetts, United States,
of Radiology, Brigham and Women's Hospital, Boston,
Massachusetts, United States
Understanding the behavior of ionic volume currents in
strong magnetic fields could facilitate efforts to use
MRI to detect signals more tightly coupled to neuronal
activity. However, studies on this topic are
controversial: two competing mechanisms have been
proposed to account for the behavior of these currents.
One of these mechanisms, magnetohydrodynamic flow,
predicts a slow evolution of phase signals (on the order
of one minute for 0.9% saline at 3T) that is dependent
on both field strength and conductivity. Here, we test
and confirm these predictions using 0.9% and 3.6% saline
current phantoms scanned at 1.5T and 3T.
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