Meeting Banner
Abstract #3109

Reducing the error: Regional effects of HRF basis functions on EEG-microstate informed fMRI

Simon Schwab 1 , Yosuke Morishima 1 , Thomas Koenig 1 , Thomas Dierks 1 , Andrea Federspiel 1 , and Kay Jann 2

1 University Hospital of Psychiatry, Department of Psychiatric Neurophysiology / University of Bern, Bern, Switzerland, 2 Department of Neurology, University of California, Los Angeles, California, United States

In the present work, we aimed to compare two sets of HRFs for microstate-informed resting-state fMRI analysis: the standard canonical HRF (CA), and the HRFs extended by the two temporal and dispersion derivatives (CA+). Fourteen healthy subjects underwent simultaneous EEG/fMRI. We have found that the extended model CA+ shows lower residuals for visual and right auditory areas across subjects. These findings provide further support that the canonical HRF alone may be insufficient to explain BOLD responses varying across brain regions and subjects. However, further investigation is needed to reduce residuals by using more flexible HRF models.

This abstract and the presentation materials are available to members only; a login is required.

Join Here