Abstract #3139
Myelin Water Fraction (MWF) Imaging using Flip angle mapping and a Dual Channel Transmit Coil at 3T
Gisela E Hagberg 1,2 , Samuel Groeschel 3 , Thomas Prasloski 4 , Alex MacKay 4 , Uwe Klose 5 , Ingeborg Krgeloh-Mann 3 , and Klaus Scheffler 1,2
1
Biomedical Magnetic Resonance, University
Hospital Tuebingen, Tuebingen, Germany, Germany,
2
High
Field Magnetic Resonance, MPI for Biological
Cybernetics, Tuebingen, Germany,
3
University
Children's Hospital, Tuebingen, Germany,
4
University
of British Columbia, Vancouver, Canada,
5
Department
ofDiagnostic and Interventional Neuroradiology,
University Hospital Tuebingen, Germany
The quality of MWF maps obtained with the standard
approach, were compared with results obtained from
measured and scaled flip angle maps in a cohort of 10
healthy young volunteers. Two scaling approaches were
used; an expected 180 degree pulse and scaling to the
first pass fitted FA. The two-step procedure was found
to be a viable approach to improve the MWF maps, without
a too high cost in terms of goodness-of-fit or
distinction between components.
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