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Abstract #3138

Liver T2* measurements: The best curve fitting model for ROI based method and Pixel based method

Monruedee Tapanya 1 , Kittichai Wantanajittikul 2 , Busakol Ngammuang 1 , Suchaya Silvilairat 3 , Suthat Fuchareon 4 , Kittiphong Paiboonsukwong 4 , and Suwit Saekho 1,2

1 Radiologic Technology, Faculty of Associated Medical Sciences, Chiang Mai University, Chiang Mai, Thailand, 2 Biomedical Engineering Center, Faculty of Engineering, Chiang Mai University, Chiang Mai, Thailand, 3 Pediatrics, Faculty of Medicine,Chiang Mai University, Chiang Mai, Thailand, 4 Thalassemia Research Center Institute of Molecular Biosciences, Mahidol University, Nakhon Pathom, Thailand

We compared between median T2*obtained from pixel based method and the T2* derived from ROI based method in 3 different fitting models, mono-exponential, Offset and Truncation model. Fifteen β thalassemia major patients were involved to this study. The results showed strongly correlation between T2* obtained from two methods with offset fitting model and there was no significant difference between the 2 methods with this fitting model. ROI based method with offset fitting model potentially provided similar T2* to that of pixel based method for liver T2* measurements.

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