Meeting Banner
Abstract #3151

Amide Proton Transfer Imaging of the Head and Neck at 3T: A Feasibility Study and preliminary results

Jing Yuan 1 , Ann D King 1 , Shuzhong Chen 1 , Kunwar S Bhatia 1 , Qinwei Zhang 1 , Tom Wing Cheung Yuen 1 , Yi-Xiang J Wang 1 , David Ka Wai Yeung 1 , Juan Wei 2 , and Jinyuan Zhou 3

1 Imaging and Interventional Radiology, The Chinese University of Hong Kong, Shatin, NT, Hong Kong, 2 Philips Research China, Shanghai, China, 3 Department of Radiology, Johns Hopkins University School of Medicine, Baltimore, Maryland, United States

This study for the first time explored the use of APT-MRI for the head and neck (HN) at 3T, which is challenging due to tissue heterogeneity, pronounced susceptibility and various motions. We successfully demonstrated the feasibility of APT-MRI for the HN at clinical field strengths by adopting various approaches for image acquisition and data processing to mitigate the technical challenges. Z-spectra and of magnetization transfer ratio asymmetry of HN tissues were recorded. Preliminary results of APT-MRI on HN tumor patients showed that APT effect would be promising to be used as a sensitive biomarker for tumor delineation and characterization.

This abstract and the presentation materials are available to members only; a login is required.

Join Here