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Abstract #3168

Investigation of White Matter Characteristics using Interslice Magnetization Transfer Ratio and Asymmetry at High Field

Jae-Woong Kim 1 , Janggeun Cho 2 , Chulhyun Lee 2 , and Sung-Hong Park 1

1 Department of Bio and Brain Engineering, Korea Advanced Institute of Science and Technology, Daejeon, Korea, 2 Korea Basic Science Institute, Ochang, Korea

Imaging myelin is important for studies related to white matter (WM) diseases. We investigated the feasibility of mapping WM characteristics using interslice MT asymmetry and MT ratio using a recent method termed Alternate Ascending/Descending Directional Navigation (ALADDIN). The WM contrast (compared to gray matter and muscle) was much higher in MT asymmetry images than in MT ratio images, and the two images showed slightly different WM information in subcortical regions, indicating that combination of MT ratio and MT asymmetry may be a promising tool for better understanding of WM characteristics.

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