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Abstract #3195

T 2 Quantification Using Only T 2 -weighted and Proton Density Weighted Fast Spin Echo Images

Kelly C McPhee 1 and Alan H Wilman 2

1 Physics, University of Alberta, Edmonton, Alberta, Canada, 2 Biomedical Engineering, University of Alberta, Edmonton, Alberta, Canada

Proton density and T 2 -weighted fast spin echo images are frequently acquired in clinical MRI exams. T 2 quantification is commonly performed in the clinic via applying an exponential fit to these two images, despite recent evidence that an exponential fit is insufficient to correctly quantify T 2 . We present T 2 quantification by implementing stimulated echo compensated T 2 fitting using only a proton density-weighted and a T 2 -weighted fast spin echo image. This method is demonstrated in the human brain in comparison to a standard quantitative multi-echo spin echo approach.

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